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Multiple Sclerosis (MS) Bundle

Bundle

Multiple Sclerosis (MS) Bundle

A focused CarePlanRx™ support resource designed to improve clarity, follow-through, and next-step confidence.

Format digital
Access $99.00
Item ID bndl-021
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Educational support only. This resource complements, not replaces, provider instructions, facility policy, or medical advice.

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A focused CarePlanRx™ support resource designed to improve clarity, follow-through, and next-step confidence.

Bundle Contents

Included in this bundle

This bundle includes the following companions, guidance resources, and workbook tools from the bundle matrix.

acd-021 Multiple Sclerosis Companion
acd-027 Sleep & Energy Recovery Companion
dcm001 Condition Overview & What to Expect
dcm003 Daily Management & Routine Planner
dcm005 Flare-Up Protocol
mwp002 Sleep Hygiene
mwp015 Focus Builder
hmb002 Self-Management Toolkit
inj002 Balance & Fall Prevention
hmb007 Goal Mapping
kpd002 Disease & Condition Management Journal
kpd004 Mental Wellness & Participation Journal
kpd008 Cognitive Endurance & Brain Fog Workbook
kpd010 Sleep Reset Workbook
kpd014 Navigating Tough Days Workbook

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Clinical Confidence

Evidence behind this resource

40 sources
Evidence-informed

Guidance is connected to the CarePlanRx™ reference database.

AMA-style references

Sources are formatted for clinical review and transparency.

Methodology available

Users can review how references support the resource framework.

View Clinical Evidence & Methodology

View clinical references 40 sources
  1. National Institute for Health and Care Excellence. Multiple sclerosis in adults: management. NICE Guideline NG220. 2022;Published June 22, 2022. https://www.nice.org.uk/guidance/ng220 Source
  2. American Occupational Therapy Association. Occupational Therapy Practice Framework: Domain and Process—Fourth Edition. American Journal of Occupational Therapy. 2020;74(Suppl 2):7412410010p1-7412410010p87. doi:10.5014/ajot.2020.74S2001 Source
  3. National Multiple Sclerosis Society. Symptoms of multiple sclerosis. National Multiple Sclerosis Society. 2026. https://www.nationalmssociety.org/understanding-ms/what-is-ms/ms-symptoms Source
  4. Smallfield S, Fang L, Kyler D. Self-management interventions to improve activities of daily living and rest and sleep for adults with chronic conditions: a systematic review. American Journal of Occupational Therapy. 2021;75(4):7504190010. doi:10.5014/ajot.2021.046946 Source
  5. National Multiple Sclerosis Society. What is MS?. National Multiple Sclerosis Society. 2026. https://www.nationalmssociety.org/understanding-ms/what-is-ms Source
  6. Fields B, Smallfield S, Marc-Aurele J, et al. Occupational therapy practice guidelines for adults with chronic conditions. American Journal of Occupational Therapy. 2022;76(2):7602397010. https://research.aota.org/ajot/article/76/2/7602397010/23263/Occupational-Therapy-Practice-Guidelines-for Source
  7. Smallfield S, Molitor WL. Occupational therapy interventions addressing sleep for community-dwelling older adults: a systematic review. American Journal of Occupational Therapy. 2018;72(4):7204190030p1-7204190030p9. doi:10.5014/ajot.2018.031211 Source
  8. American Academy of Neurology. Disease-modifying therapies for adults with multiple sclerosis. American Academy of Neurology Practice Guideline. 2018;Reaffirmed October 19, 2024. https://www.aan.com/Guidelines/home/GuidelineDetail/898 Source
  9. Kim JY, Lee J, Park HY. Exploring occupation-based interventions for sleep within occupational therapy practice framework: a systematic review. Healthcare. 2026. https://pmc.ncbi.nlm.nih.gov/articles/PMC12935297/ Source
  10. U.S. Department of Veterans Affairs. Disease modifying therapies in multiple sclerosis. VA Pharmacy Benefits Management Clinical Recommendations. 2024;Revised June 2024. https://www.va.gov/formularyadvisor/DOC_PDF/CRE_Disease_Modifying_Therapies_in_Multiple_Sclerosis_Rev_June_2024.pdf Source
  11. Multiple Sclerosis Society UK. Signs and symptoms of MS. MS Society UK. 2025. https://www.mssociety.org.uk/about-ms/signs-and-symptoms Source
  12. Ramar K, Malhotra RK, Carden KA, et al. Sleep is essential to health: an American Academy of Sleep Medicine position statement. Journal of Clinical Sleep Medicine. 2021;17(10):2115-2119. doi:10.5664/jcsm.9476 Source
  13. Multiple Sclerosis Association of America. The symptoms of MS. Multiple Sclerosis Association of America. 2025;Updated April 30, 2025. https://mymsaa.org/publications/about-ms/symptoms/ Source
  14. Watson NF, Badr MS, Belenky G, et al. Recommended amount of sleep for a healthy adult: a joint consensus statement of the American Academy of Sleep Medicine and Sleep Research Society. Sleep. 2015;38(6):843-844. doi:10.5665/sleep.4716 Source
  15. National Multiple Sclerosis Society. Heat and temperature sensitivity. National Multiple Sclerosis Society. 2025. https://www.nationalmssociety.org/managing-ms/living-with-ms/diet-exercise-and-healthy-behaviors/heat-temperature Source
  16. Edinger JD, Arnedt JT, Bertisch SM, et al. Behavioral and psychological treatments for chronic insomnia disorder in adults: an American Academy of Sleep Medicine clinical practice guideline. Journal of Clinical Sleep Medicine. 2021;17(2):255-262. doi:10.5664/jcsm.8986 Source
  17. Walker J, Muench A, Perlis ML, Vargas I. Cognitive behavioral therapy for insomnia: a primer. Clinical Psychology Review. 2022;92:102116. doi:10.1016/j.cpr.2022.102116 Source
  18. Multiple Sclerosis Council for Clinical Practice Guidelines. Fatigue and multiple sclerosis: evidence-based management strategies for fatigue in multiple sclerosis. Paralyzed Veterans of America Clinical Practice Guideline. 1998;Clinical practice guideline. https://pva.org/wp-content/uploads/2021/09/fatigue1b772.pdf Source
  19. Asano M, Finlayson ML. Meta-analysis of three different types of fatigue management interventions for people with multiple sclerosis: exercise, education, and medication. Multiple Sclerosis International. 2014;2014:798285. doi:10.1155/2014/798285 Source
  20. Carney CE, Buysse DJ, Ancoli-Israel S, et al. The consensus sleep diary: standardizing prospective sleep self-monitoring. Sleep. 2012;35(2):287-302. doi:10.5665/sleep.1642 Source
  21. Kim S, Xu Y, Dore K, Gewurtz R, Larivière N, Letts L. Fatigue self-management led by occupational therapists and/or physiotherapists for chronic conditions: a systematic review and meta-analysis. Chronic Illness. 2022;18(4):781-793. doi:10.1177/17423953211039783 Source
  22. Dalgas U, Stenager E, Ingemann-Hansen T. Multiple sclerosis and physical exercise: recommendations for the application of resistance-, endurance- and combined training. Multiple Sclerosis. 2008;14(1):35-53. doi:10.1177/1352458507079445 Source
  23. Alizadeh N, Lix L, Finlayson M. What we know about fatigue self-management programs for people with chronic conditions: a scoping review. Patient Education and Counseling. 2023;112:107728. doi:10.1016/j.pec.2023.107728 Source
  24. Kalb R, Brown TR, Coote S, et al. Exercise and lifestyle physical activity recommendations for people with multiple sclerosis throughout the disease course. Multiple Sclerosis Journal. 2020;26(12):1459-1469. doi:10.1177/1352458520915629 Source
  25. American Physical Therapy Association. Physical therapy guide to multiple sclerosis. ChoosePT. 2025;Updated October 23, 2025. https://www.choosept.com/guide/physical-therapy-guide-multiple-sclerosis Source
  26. Omura KM, Faria-Fortini I, Polese JC, et al. Energy conservation, minimum steps, and adaptations when using energy conservation strategies: a scoping review. Hong Kong Journal of Occupational Therapy. 2022;35(2):93-107. doi:10.1177/15691861221137223 Source
  27. Fateh HR, Merghati-Khoei E, Latifi S, et al. The effect of energy conservation strategies on fatigue, occupational performance, and quality of life in people with multiple sclerosis: a randomized controlled trial. Iranian Journal of Neurology. 2022;21(4):178-186. https://pmc.ncbi.nlm.nih.gov/articles/PMC9716468/ Source
  28. Yu CH, Mathiowetz V. Occupational therapy practice guidelines for adults with multiple sclerosis. American Journal of Occupational Therapy. 2022;76(5):7605397010. doi:10.5014/ajot.2022.76S501 Source
  29. Sanal-Hayes NEM, Mclaughlin M, Hayes LD, et al. A scoping review of pacing for management of myalgic encephalomyelitis/chronic fatigue syndrome. Journal of Translational Medicine. 2023;21:720. doi:10.1186/s12967-023-04587-5 Source
  30. Khan F, Amatya B. Rehabilitation in multiple sclerosis: a systematic review of systematic reviews. Archives of Physical Medicine and Rehabilitation. 2017;98(2):353-367. doi:10.1016/j.apmr.2016.04.016 Source
  31. National Institute for Health and Care Excellence. Myalgic encephalomyelitis/chronic fatigue syndrome: diagnosis and management. NICE guideline NG206. NICE Guideline. 2021;NG206. https://www.nice.org.uk/guidance/ng206 Source
  32. Bethoux F. Spasticity management in multiple sclerosis. Continuum. 2016;22(3):882-893. doi:10.1212/CON.0000000000000335 Source
  33. Kingdon C, Giotas M, Nacul L, Lacerda E. Healthcare professionals’ understanding of the new NICE guideline for ME/CFS: implications for practice. Healthcare (Basel). 2022;10(5):898. doi:10.3390/healthcare10050898 Source
  34. Kister I, Bacon TE, Chamot E, et al. Natural history of multiple sclerosis symptoms. International Journal of MS Care. 2013;15(3):146-156. doi:10.7224/1537-2073.2012-053 Source
  35. Bull FC, Al-Ansari SS, Biddle S, et al. World Health Organization 2020 guidelines on physical activity and sedentary behaviour. British Journal of Sports Medicine. 2020;54(24):1451-1462. doi:10.1136/bjsports-2020-102955 Source
  36. Benedict RHB, Amato MP, DeLuca J, Geurts JJG. Cognitive impairment in multiple sclerosis: clinical management, MRI, and therapeutic avenues. Lancet Neurology. 2020;19(10):860-871. doi:10.1016/S1474-4422(20)30277-5 Source
  37. McCowan A, McNamara RJ, McKeough ZJ. Occupational therapy in adults with chronic respiratory conditions: a scoping review. Australian Occupational Therapy Journal. 2023;70(5):520-533. doi:10.1111/1440-1630.12861 Source
  38. Boeschoten RE, Braamse AMJ, Beekman ATF, et al. Prevalence of depression and anxiety in multiple sclerosis: a systematic review and meta-analysis. Journal of the Neurological Sciences. 2017;372:331-341. doi:10.1016/j.jns.2016.11.067 Source
  39. Winkelman JW, Berkowski JA, DelRosso LM, et al. Treatment of restless legs syndrome and periodic limb movement disorder: an American Academy of Sleep Medicine clinical practice guideline. Journal of Clinical Sleep Medicine. 2025;21(1):137-152. doi:10.5664/jcsm.11390 Source
  40. Smallfield S, Fang L, Kyler D. Self-management interventions to improve activities of daily living and rest and sleep for adults with chronic conditions: a systematic review. American Journal of Occupational Therapy. 2021;75(4):7504190010. doi:10.5014/ajot.2021.046946 Source

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